What is the most important factor for a fulfilling life according to science and spirituality?

A fulfilling life, according to spirituality, is to live a life of peace and purpose, not to run after pleasure. So spirituality teaches us to evolve from achievement to fulfillment and to enlightenment. And what does science say? Science talks about a state of being, a state of being where there is no mental illness. Even science talks about silence and stillness. Science talks about how we should meditate. And this is the way to overcome all misery and stress. Our life will not be a mess, if only we realize, ‘Who am I?’ and that is a spiritual answer. Both will lead us to happiness.