Do you recommend ever moving away from where you’re from or have been your whole life?

Lately I’ve really been considering moving away from the place I was born and raised and have been for all of my 28 years. I’ve traveled to a few places in the states, the furthest being Colorado but am not what you’d call a well versed traveler. I’m pretty close to the blue ridge parkway in a really small and pretty conservative town. My family is here, but my mom and my best friend are really the only person I would miss. Do you recommend living away from your home town? Why or why not?